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dc.contributor.authorLin, Ching-Changen_US
dc.contributor.authorSun, Da-Shiuanen_US
dc.contributor.authorLin, Ya-Linen_US
dc.contributor.authorTsai, Tsung-Tsoen_US
dc.contributor.authorCheng, Chiehen_US
dc.contributor.authorSun, Wen-Hsienen_US
dc.contributor.authorKo, Fu-Hsiangen_US
dc.date.accessioned2017-04-21T06:56:34Z-
dc.date.available2017-04-21T06:56:34Z-
dc.date.issued2017-04-15en_US
dc.identifier.issn0956-5663en_US
dc.identifier.urihttp://dx.doi.org/10.1016/j.bios.2016.12.011en_US
dc.identifier.urihttp://hdl.handle.net/11536/133122-
dc.description.abstractA flexible and miniaturized metal semiconductor metal (MSM) biomolecular photodetector was developed as the core photocurrent system through chemiluminescence for hydrogen peroxide sensing. The flexible photocurrent sensing system was manufactured on a 30-mu m-thick crystalline silicon chip by chemical etching process, which produced a flexible silicon chip. A surface texturization design on the flexible device enhanced the light-trapping effect and minimized reflectivity losses from the incident light. The model protein streptavidin bound to horseradish peroxidase (HRP) was successfully immobilized onto the sensor surface through high-affinity conjugation with biotin. The luminescence reaction occurred with luminol, hydrogen peroxide and HRP enzyme, and the emission of light from the catalytic reaction was detected by underlying flexible photodetector. The chemiluminescence in the miniaturized photocurrent sensing system was successfully used to determine the hydrogen peroxide concentration in real-time analyses. The hydrogen peroxide detection limit of the flexible MSM photodetector was 2.47 mM. The performance of the flexible MSM photodetector maintained high stability under bending at various bending radii. Moreover, for concave bending, a significant improvement in detection signal intensity (14.5% enhancement compared with a flat configuration) was observed because of the increased photocurrent, which was attributed to enhancement of light trapping. Additionally, this detector was used to detect hydrogen peroxide concentrations in commercial hair dye products, which is a significant issue in the healthcare field. The development of this novel, flexible and miniaturized MSM biomolecular photodetector with excellent mechanical flexibility and high sensitivity demonstrates the applicability of this approach to future wearable sensor development efforts.en_US
dc.language.isoen_USen_US
dc.subjectFlexibleen_US
dc.subjectMSM photodetectoren_US
dc.subjectChemiluminescenceen_US
dc.subjectHydrogen peroxideen_US
dc.subjectHair dye sensoren_US
dc.titleA flexible and miniaturized hair dye based photodetector via chemiluminescence pathwayen_US
dc.identifier.doi10.1016/j.bios.2016.12.011en_US
dc.identifier.journalBIOSENSORS & BIOELECTRONICSen_US
dc.citation.volume90en_US
dc.citation.spage349en_US
dc.citation.epage355en_US
dc.contributor.department材料科學與工程學系zh_TW
dc.contributor.departmentDepartment of Materials Science and Engineeringen_US
dc.identifier.wosnumberWOS:000392768000048en_US
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