標題: Efficacies of treatments for anti-NMDA receptor encephalitis
作者: Wang, Hsiuying
統計學研究所
Institute of Statistics
關鍵字: Anti-NMDA Receptor Encephalitis;Treatment;Efficacy Rate
公開日期: 1-Jan-2016
摘要: Treatments for anti-N-methyl-D-aspartate (NMDA) receptor encephalitis include immunotherapy with steroids, intravenous immunoglobulin, plasma exchange, or plasmapheresis as first-line treatments, immunotherapy with rituximab or cyclophosphamide as second-line treatments, and tumor removal. In this systematic review, we evaluated previous studies and examined the association between certain microRNAs and anti-NMDA receptor encephalitis to investigate the performance of different treatment combinations. The efficacies of different combinations of treatments classified into the following four categories were compared: (I) intravenous immunoglobulin administration, (II) plasmapheresis or plasma exchange, (III) treatment with rituximab or cyclophosphamide and (IV) tumor removal. Statistical analyses showed that treatment combinations including at least two of these categories resulted in higher efficacy rates than treatment with a single form of therapy. These findings suggest that if a patient is not recovering, converting to other therapies is more likely to result in early recovery than continuing on the original therapy.
URI: http://dx.doi.org/10.2741/4412
http://hdl.handle.net/11536/134179
ISSN: 1093-9946
DOI: 10.2741/4412
期刊: FRONTIERS IN BIOSCIENCE-LANDMARK
Volume: 21
起始頁: 651
結束頁: 663
Appears in Collections:Articles