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dc.contributor.authorLee, Mon-Juanen_US
dc.contributor.authorSung, Yu-Chienen_US
dc.contributor.authorHsiao, Yu-Chengen_US
dc.contributor.authorLee, Weien_US
dc.date.accessioned2019-04-03T06:47:17Z-
dc.date.available2019-04-03T06:47:17Z-
dc.date.issued2016-01-01en_US
dc.identifier.isbn978-1-5106-0271-7; 978-1-5106-0272-4en_US
dc.identifier.issn0277-786Xen_US
dc.identifier.urihttp://dx.doi.org/10.1117/12.2236774en_US
dc.identifier.urihttp://hdl.handle.net/11536/136393-
dc.description.abstractThe texture observation has long been the core technique in liquid crystal (LC)-based bioassays. Its working principle stems from the dark-to-bright texture change induced by the interruption of the initially homeotropic alignment in nematic bulks or from the radial-to-bipolar configuration transition in LC droplets in the presence of biomolecules. One of the drawbacks of this observational scheme, which requires a polarizing optical microscope, is the difficulty in quantitative analysis. In this invited paper, we report on our recent development of alternative optical biosensing techniques based on cholesteric LCs (CLCs) without the use of a polarizer. The increase in structural order in a vertically anchored CLC cell in the quasi-planar state provides a means to allow detection and quantification of the concentration of biomolecules immobilized on the interface between the mesophase and the surfactant DMOAP for LC vertical alignment.en_US
dc.language.isoen_USen_US
dc.subjectLiquid crystalsen_US
dc.subjectCholesteric liquid crystalsen_US
dc.subjectTransmission spectroscopyen_US
dc.subjectBiophotonicsen_US
dc.subjectBiosensorsen_US
dc.titleChiral liquid crystals as biosensing platformsen_US
dc.typeProceedings Paperen_US
dc.identifier.doi10.1117/12.2236774en_US
dc.identifier.journalLIQUID CRYSTALS XXen_US
dc.citation.volume9940en_US
dc.citation.spage0en_US
dc.citation.epage0en_US
dc.contributor.department影像與生醫光電研究所zh_TW
dc.contributor.departmentInstitute of Imaging and Biomedical Photonicsen_US
dc.identifier.wosnumberWOS:000389681100016en_US
dc.citation.woscount0en_US
Appears in Collections:Conferences Paper


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