標題: | Efg1 involved in drug resistance by regulating the expression of ERG3 in Candida albicans |
作者: | Lo, HJ Wang, JS Lin, CY Chen, CG Hsiao, TY Hsu, CT Su, CL Fann, MJ Ching, YT Yang, YL 生物科技學系 資訊工程學系 Department of Biological Science and Technology Department of Computer Science |
公開日期: | 1-Mar-2005 |
摘要: | The ERG3 gene in Candida albicans was identified as a gene whose mRNA level was higher in the cph1/cph1 efg1/efg1 double mutant than in the wild-type cells. Further study showed that Efg1, but not Cph1, negatively regulated ERG3. Mutations in EFG1 consistently increased the susceptibility of the cells to antifungal agents. |
URI: | http://dx.doi.org/10.1128/AAC.49.3.1213-1215.2005 http://hdl.handle.net/11536/13933 |
ISSN: | 0066-4804 |
DOI: | 10.1128/AAC.49.3.1213-1215.2005 |
期刊: | ANTIMICROBIAL AGENTS AND CHEMOTHERAPY |
Volume: | 49 |
Issue: | 3 |
起始頁: | 1213 |
結束頁: | 1215 |
Appears in Collections: | Articles |
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