標題: Accurate real-time sensing tip for aqueous NO with optical fibers embedded in active hydrogel waveguide
作者: Chung, Chieh-Wen
Tsai, May-Jywan
Lin, Peng-Wei
Huang, Ding-Wen
Wang, Kuan-Hsun
Chen, Yu-An
Meng, Hsin-Fei
Zan, Hsiao-Wen
Cheng, Henrich
Tong, Limin
Zhang, Lei
Horng, Sheng-Fu
Hung, Cheng-Hsiung
分子醫學與生物工程研究所
物理研究所
光電工程學系
Institute of Molecular Medicine and Bioengineering
Institute of Physics
Department of Photonics
公開日期: 1-Feb-2018
摘要: A NO sensing tip is made by inserting two parallel optical fibers inside a poly 2-hydroxyethyl methacrylate (PolyHEMA) hydrogel waveguide mixed with the probe molecule 1, 2-Diaminoanthraquinone (DAQ). There is a length difference of 1 mm between the two fibers, and the light has to propagate through the difference from the short fiber to the long fiber. The total cross section area of the active hydrogel waveguide embedded with the fibers is only 3mm x 1.2 mm. For practical use the tip is housed in a needle for mechanical protection and the sensing tip is able to detect aqueous NO concentration around 1 mu M with time resolution about 5 minutes. Such a sensing tip can be used to monitor the medical conditions inside the brain after a stroke or a brain injury. (C) 2018 Author(s).
URI: http://dx.doi.org/10.1063/1.4994231
http://hdl.handle.net/11536/144626
ISSN: 2158-3226
DOI: 10.1063/1.4994231
期刊: AIP ADVANCES
Volume: 8
Appears in Collections:Articles