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dc.contributor.authorLin, C. C.en_US
dc.contributor.authorChen, Y. W.en_US
dc.contributor.authorHsiao, C. S.en_US
dc.contributor.authorChen, S. Y.en_US
dc.date.accessioned2018-08-21T05:54:29Z-
dc.date.available2018-08-21T05:54:29Z-
dc.date.issued2017-01-01en_US
dc.identifier.issn0272-8842en_US
dc.identifier.urihttp://dx.doi.org/10.1016/j.ceramint.2017.05.299en_US
dc.identifier.urihttp://hdl.handle.net/11536/146025-
dc.description.abstractWe developed a novel electro-responsive drug delivery device by depositing fluorescein isothiocyanate (FITC)-loaded zinc oxide nanotubes (ZTs) onto indium tin oxide (ITO)/polyethylene terephthalate (PET) substrates (called FITC-ZTs-ITO/PET). With a large payload of FITC up to 0.98 mmol g(-1), the FITC-ZTs simultaneously provide a burst-like FITC release and a repeated step-like release after application of an electrical field at specific resonant frequencies. Additionally, FITC-ZTs-ITO/PET is biocompatible with both HeLa and MRC5 cells for ZT concentrations below 50 mu g/ml. These results demonstrate that FITC-ZTs-ITO/PET is a new platform that can provide local, on-demand electrically responsive drug release for biomedical applications.en_US
dc.language.isoen_USen_US
dc.subjectZnO nanotubeen_US
dc.subjectDrug releaseen_US
dc.subjectElectrically responsiveen_US
dc.subjectNanoresonatorsen_US
dc.titleElectrically responsive ZnO nanotubes for controlled release of biomoleculesen_US
dc.typeArticleen_US
dc.identifier.doi10.1016/j.ceramint.2017.05.299en_US
dc.identifier.journalCERAMICS INTERNATIONALen_US
dc.citation.volume43en_US
dc.citation.issue1en_US
dc.contributor.department材料科學與工程學系zh_TW
dc.contributor.departmentDepartment of Materials Science and Engineeringen_US
dc.identifier.wosnumberWOS:000409285800137en_US
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