標題: Design of a 0.5V 1.68mW Nose-on-a-Chip for Rapid Screen of Chronic Obstructive Pulmonary Disease
作者: Chou, Ting-I
Chiu, Shih-Wen
Chang, Kwuang-Han
Chen, Yi-Ju
Tang, Chen-Ting
Shih, Chung-Hung
Hsieh, Chih-Cheng
Chang, Meng-Fan
Yang, Chia-Hsiang
Chiueh, Herming
Tang, Kea-Tiong
電子工程學系及電子研究所
電機工程學系
Department of Electronics Engineering and Institute of Electronics
Department of Electrical and Computer Engineering
關鍵字: COPD;Nose-on-a-chip system;SoC
公開日期: 1-Jan-2016
摘要: Chronic obstructive pulmonary disease (COPD) still lacks a rapid diagnosis strategy. In this paper, we propose a low-power nose-on-a-chip for rapid COPD screening. This chip is designed for implementation in a personal handheld device that detects patient breath for COPD diagnosis. The chip has 36 on-chip sensors, a 36-channel adaptive interface with an integrated programmable amplifier, a four-channel frequency readout interface, one on-chip temperature sensor, a two-channel successive approximation analog-to-digital converter, a scalable learning kernel cluster, and a reduced instruction set computing core with low-voltage static random-access memory. This chip is fabricated in 90 nm CMOS and consumes 1.68 mW at 0.5 V. In simulation, the system distinguished between undiseased and diseased patients with 90.82% accuracy for a set of diseases including COPD and asthma and exhibited 92.31% accuracy for identifying patients with COPD or asthma. The system classified severity levels of COPD under four labels (normal, mild, moderate, and severe) with 92.00% accuracy. Accordingly, this work provides a promising solution for the unmet medical need of rapid COPD screening.
URI: http://hdl.handle.net/11536/146568
ISSN: 2163-4025
期刊: PROCEEDINGS OF 2016 IEEE BIOMEDICAL CIRCUITS AND SYSTEMS CONFERENCE (BIOCAS)
起始頁: 592
結束頁: 595
Appears in Collections:Conferences Paper