標題: | Design of a 0.5V 1.68mW Nose-on-a-Chip for Rapid Screen of Chronic Obstructive Pulmonary Disease |
作者: | Chou, Ting-I Chiu, Shih-Wen Chang, Kwuang-Han Chen, Yi-Ju Tang, Chen-Ting Shih, Chung-Hung Hsieh, Chih-Cheng Chang, Meng-Fan Yang, Chia-Hsiang Chiueh, Herming Tang, Kea-Tiong 電子工程學系及電子研究所 電機工程學系 Department of Electronics Engineering and Institute of Electronics Department of Electrical and Computer Engineering |
關鍵字: | COPD;Nose-on-a-chip system;SoC |
公開日期: | 1-Jan-2016 |
摘要: | Chronic obstructive pulmonary disease (COPD) still lacks a rapid diagnosis strategy. In this paper, we propose a low-power nose-on-a-chip for rapid COPD screening. This chip is designed for implementation in a personal handheld device that detects patient breath for COPD diagnosis. The chip has 36 on-chip sensors, a 36-channel adaptive interface with an integrated programmable amplifier, a four-channel frequency readout interface, one on-chip temperature sensor, a two-channel successive approximation analog-to-digital converter, a scalable learning kernel cluster, and a reduced instruction set computing core with low-voltage static random-access memory. This chip is fabricated in 90 nm CMOS and consumes 1.68 mW at 0.5 V. In simulation, the system distinguished between undiseased and diseased patients with 90.82% accuracy for a set of diseases including COPD and asthma and exhibited 92.31% accuracy for identifying patients with COPD or asthma. The system classified severity levels of COPD under four labels (normal, mild, moderate, and severe) with 92.00% accuracy. Accordingly, this work provides a promising solution for the unmet medical need of rapid COPD screening. |
URI: | http://hdl.handle.net/11536/146568 |
ISSN: | 2163-4025 |
期刊: | PROCEEDINGS OF 2016 IEEE BIOMEDICAL CIRCUITS AND SYSTEMS CONFERENCE (BIOCAS) |
起始頁: | 592 |
結束頁: | 595 |
Appears in Collections: | Conferences Paper |