標題: Correlation between Basal Macular Circulation and Following Glaucomatous Damage in Progressed High-Tension and Normal-Tension Glaucoma
作者: Lee, Chia-Yi
Liu, Chin-Hsing
Chen, Hung-Chi
Sun, Chi-Chin
Yao, Yen-Po
Chao, Shih-Chun
電機工程學系
Department of Electrical and Computer Engineering
關鍵字: Glaucoma;Normal-tension glaucoma;Optical coherence tomography angiography;Macula;Vessel density;Retinal nerve fiber layer;Ganglion cell complex
公開日期: 1-一月-2019
摘要: Objectives: Evaluate the correlation between basal macular circulation and late structural damage in progressed high-tension glaucoma (HTG) and normal-tension glaucoma (NTG) via optical coherence tomography angiography (OCTA). Methods: Patients who received an OCTA examination were divided into progressed HTG, progressed NTG, and well-controlled HTG (control) groups. Superficial macular vessel density (SmVD), deep macular vessel density (DmVD), foveal avascular zone (FAZ), and flow area of the outer retina and choriocapillaris were obtained by one OCTA device. Associations between macular angiography and glaucoma parameters, including the visual field, retinal nerve fiber layer, and ganglion cell complex, were analyzed. Results: A total of 60 eyes from 60 patients were enrolled. The progressed HTG and NTG groups had lower SmVD than the control group, while the progressed NTG group had lower DmVD and a larger FAZ than the control group. The flow area of the outer retina in the progressed HTG group was lower than that of the control. A significant correlation between SmVD and glaucoma parameters was found in the progressed HTG group, while a similar correlation between SmVD and DmVD to glaucoma parameters was observed in the progressed NTG group. Conclusion: The progressed HTG and NTG patients showed an impaired vascular intake before significant disease development compared to well-controlled cases.
URI: http://dx.doi.org/10.1159/000499695
http://hdl.handle.net/11536/152237
ISSN: 0030-3747
DOI: 10.1159/000499695
期刊: OPHTHALMIC RESEARCH
Volume: 62
Issue: 1
起始頁: 46
結束頁: 54
顯示於類別:期刊論文