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dc.contributor.authorWu, Yen-Kuen_US
dc.contributor.authorRawal, Viresh H.en_US
dc.date.accessioned2019-12-13T01:09:53Z-
dc.date.available2019-12-13T01:09:53Z-
dc.date.issued2019-10-21en_US
dc.identifier.issn1477-0520en_US
dc.identifier.urihttp://dx.doi.org/10.1039/c9ob01880hen_US
dc.identifier.urihttp://hdl.handle.net/11536/153005-
dc.description.abstractDescribed is a one-flask, two-step method for the synthesis of highly functionalized piperidines. The process involves formal [4 + 2] cycloadditions of Schiff bases and Nazarov reagents, followed by facile elaborations of the initial cycloadducts. Notably, these aza-annulations are facilitated by protic solvents and proceed smoothly under ambient conditions, without other additives. The synthetic utility of this annulation protocol is further showcased through a concise, convergent synthesis of (+/-)-tetrabenazine.en_US
dc.language.isoen_USen_US
dc.titleRapid construction of tetrahydropyridine scaffolds via formal imino Diels-Alder reactions of Schiff bases and Nazarov reagentsen_US
dc.typeArticleen_US
dc.identifier.doi10.1039/c9ob01880hen_US
dc.identifier.journalORGANIC & BIOMOLECULAR CHEMISTRYen_US
dc.citation.volume17en_US
dc.citation.issue39en_US
dc.citation.spage8827en_US
dc.citation.epage8831en_US
dc.contributor.department應用化學系zh_TW
dc.contributor.departmentDepartment of Applied Chemistryen_US
dc.identifier.wosnumberWOS:000489910100006en_US
dc.citation.woscount0en_US
Appears in Collections:Articles