標題: Invasiveness and surgical timing evaluation by clinical features of ground-glass opacity nodules in lung cancers
作者: Chen, Pai-Hsi
Chang, Kuo-Ming
Tseng, Wei-Chi
Chen, Chien-Hung
Chao, Jui-I
交大名義發表
生物科技學系
分子醫學與生物工程研究所
National Chiao Tung University
Department of Biological Science and Technology
Institute of Molecular Medicine and Bioengineering
關鍵字: Ground-glass opacity;invasiveness;lung adenocarcinoma;surgical intervention
公開日期: 1-Jan-1970
摘要: Background The early stages of lung cancer with ground-glass opacity (GGO) pattern are detectable. However, it remains a challenge for physicians how best to treat GGO nodules as invasive tumors are occasionally found, even in pure GGO nodules. This study identified the invasiveness by the clinical features of the GGO nodules. Methods A retrospective review of patients with resected GGO nodules from August 2015 to February 2019 was performed. A total of 92 patients were enrolled and gender, age, tumor location, operation times, tumor size, histopathologic and radiological findings were analyzed. Results In this study, the sequential of GGO nodules invasiveness was significantly related to the tumor size and solid component. After regrouping the population into preinvasive and invasive groups, the invasiveness was significantly related to tumor size, solid component, tumor volume and maximal computed tomography (CT) value. Conclusions The invasiveness is difficult to evaluate according to the CT features only when the GGO nodules are less than 2 cm and consolidation/tumor ratio (C/T ratio) are less than 0.25. Tumor size and solid component are significant factors for predicting invasiveness. Part-solid GGO nodules with a diameter greater than 1 cm require surgical consideration due to their high risk of invasiveness.
URI: http://dx.doi.org/10.1111/1759-7714.13199
http://hdl.handle.net/11536/153043
ISSN: 1759-7706
DOI: 10.1111/1759-7714.13199
期刊: THORACIC CANCER
起始頁: 0
結束頁: 0
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