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dc.contributor.authorLin, Bo-Rongen_US
dc.contributor.authorChen, Chien-Hsuen_US
dc.contributor.authorChang, Chun-Hsiangen_US
dc.contributor.authorKunuku, Srinivasuen_US
dc.contributor.authorChen, Tzung-Yuangen_US
dc.contributor.authorHsiao, Tung-Yuanen_US
dc.contributor.authorYu, Hung-Kaien_US
dc.contributor.authorChang, Yu-Jenen_US
dc.contributor.authorLiao, Li-Chuanen_US
dc.contributor.authorChen, Fang-Hsinen_US
dc.contributor.authorNiu, Huanen_US
dc.contributor.authorLee, Chien-Pingen_US
dc.date.accessioned2019-12-13T01:10:01Z-
dc.date.available2019-12-13T01:10:01Z-
dc.date.issued2019-12-11en_US
dc.identifier.issn0022-3727en_US
dc.identifier.urihttp://dx.doi.org/10.1088/1361-6463/ab41e8en_US
dc.identifier.urihttp://hdl.handle.net/11536/153082-
dc.description.abstractAlthough nanodiamonds have long being considered as a potential tool for biomedical research, the practical in vivo magnetic resonance imaging (MRI) application of nanodiamonds remains relatively unexplored. In this paper, we present the first application of in vivo MRI contrast enhancement using only iron embedded magnetic nanodiamonds. An MR image enhancement was clearly demonstrated in the rendering of T2-weighted images of mice obtained using an unmodified commercial MRI scanner. The excellent contrast obtained using these nanodiamonds opens the door to the non-invasive in vivo tracking of nanodiamonds and image enhancement. In the future, one can apply these magnetic nanodiamonds together with surface modifications to facilitate drug delivery, targeted therapy, localized thermal treatment, and diagnostic imaging.en_US
dc.language.isoen_USen_US
dc.subjectironen_US
dc.subjectnanodiamondsen_US
dc.subjection implantationen_US
dc.subjectin vivoen_US
dc.subjectmrien_US
dc.subjectcontrast enhancementen_US
dc.titleIron embedded magnetic nanodiamonds for in vivo MRI contrast enhancementen_US
dc.typeArticleen_US
dc.identifier.doi10.1088/1361-6463/ab41e8en_US
dc.identifier.journalJOURNAL OF PHYSICS D-APPLIED PHYSICSen_US
dc.citation.volume52en_US
dc.citation.issue50en_US
dc.citation.spage0en_US
dc.citation.epage0en_US
dc.contributor.department電子工程學系及電子研究所zh_TW
dc.contributor.departmentDepartment of Electronics Engineering and Institute of Electronicsen_US
dc.identifier.wosnumberWOS:000488085300002en_US
dc.citation.woscount0en_US
Appears in Collections:Articles