標題: Hydrogen Bonding-Induced H-Aggregation for Fluorescence Turn-On of the GFP Chromophore: Supramolecular Structural Rigidity
作者: Tsai, Meng-Shiue
Tsai, Sung-Yu
Huang, Yi-Fan
Wang, Chien-Lung
Sun, Shih-Sheng
Yang, Jye-Shane
應用化學系
Department of Applied Chemistry
關鍵字: aggregation;fluorescence;gels;hydrogen bonds;supramolecular chemistry
公開日期: 1-Jan-1970
摘要: To turn on the fluorescence of the native green fluorescence protein (GFP) chromophore, 4-hydroxybenzylidene-dimethylimidazolinone (HBDI), in an artificial supramolecular system has been a challenging task, because it requires high local environmental rigidity. This work shows that the formation of H-aggregates of an HBDI-containing organogelator results in two orders of magnitude fluorescence enhancement (phi(f)=2.9 vs. 0.02 %), in which the inter-HBDI OH...OH H-bonds play a crucial role. The aggregation-induced fluorescence enhancement of HBDI has important implications on the origin of the high fluorescence quantum efficiency of HBDI in the GFP beta-barrel and on the supramolecular strategy for a full fluorescence recovery of HBDI. These results reveal a new approach to designing rigid chromophore aggregates for high-performance optoelectronic properties.
URI: http://dx.doi.org/10.1002/chem.202000358
http://hdl.handle.net/11536/154217
ISSN: 0947-6539
DOI: 10.1002/chem.202000358
期刊: CHEMISTRY-A EUROPEAN JOURNAL
起始頁: 0
結束頁: 0
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