標題: Microfluidics and Nanomaterial-based Technologies for Circulating Tumor Cell Isolation and Detection
作者: Cheng, Sheng-Jen
Hsieh, Kuan Yu
Chen, Shiue-Luen
Chen, Chong-You
Huang, Chien-Yu
Tsou, Hung-I
Kumar, Priyank V.
Hsieh, Jason Chia-Hsun
Chen, Guan-Yu
生物科技學系
生醫工程研究所
電機學院
Department of Biological Science and Technology
Institute of Biomedical Engineering
College of Electrical and Computer Engineering
關鍵字: liquid biopsy;circulating tumor cells;microfluidic;graphene oxide;surface modification
公開日期: 1-Apr-2020
摘要: Cancer has been one of the leading causes of death globally, with metastases and recurrences contributing to this result. The detection of circulating tumor cells (CTCs), which have been implicated as a major population of cells that is responsible for seeding and migration of tumor sites, could contribute to early detection of metastasis and recurrences, consequently increasing the chances of cure. This review article focuses on the current progress in microfluidics technology in CTCs diagnostics, extending to the use of nanomaterials and surface modification techniques for diagnostic applications, with an emphasis on the importance of integrating microchannels, nanomaterials, and surface modification techniques in the isolating and detecting of CTCs.
URI: http://dx.doi.org/10.3390/s20071875
http://hdl.handle.net/11536/154613
DOI: 10.3390/s20071875
期刊: SENSORS
Volume: 20
Issue: 7
起始頁: 0
結束頁: 0
Appears in Collections:Articles