標題: Miniaturized Cortex Cooling Device and System for Hypothermia Therapy Application on Freely Moving Rat
作者: Chang, Chih-Wei
Hou, Kuan-Chou
Chou, Lei-Chun
Chiou, Jin-Chern
Chiou, Jin-Chern
Duann, Jeng-Ren
Tsai, Yun-Wen
電機工程學系
Department of Electrical and Computer Engineering
公開日期: 2012
摘要: This paper presents a miniaturized brain cortex cooling device and system using thermoelectric (TE) cooler for hypothermia therapy application on freely moving rat. Two type of cooling electrodes including planar and micro-needle structures are fabricated and studied by EEG recording. Comparing to prior arts, our approach can be applied under freely moving behavior. The cooling temperature is designed as 2 degrees C to avoid permanent injury in brain. Packaged planar or needle electrode with TE cooler consumes only 2x2mm2. EEG recording electrodes and thermocouple are implanted for observation as well. Simulation result shows that TE-cooler with needle type electrode behaves deeper effective cooling depth and faster cooling response in rodent cortex range (similar to 2mm deep). Long term EEG monitoring on freely moving rat also presents no extra side effects with continuously cooling.
URI: http://hdl.handle.net/11536/21623
ISBN: 978-1-4577-1766-6
ISSN: 1930-0395
期刊: 2012 IEEE SENSORS PROCEEDINGS
起始頁: 1834
結束頁: 1837
Appears in Collections:Conferences Paper