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dc.contributor.authorChen, Li-Hsunen_US
dc.contributor.authorChang, Chia-Maoen_US
dc.contributor.authorSalunke, Deepak B.en_US
dc.contributor.authorSun, Chung-Mingen_US
dc.date.accessioned2014-12-08T15:30:45Z-
dc.date.available2014-12-08T15:30:45Z-
dc.date.issued2011-07-01en_US
dc.identifier.issn2156-8952en_US
dc.identifier.urihttp://dx.doi.org/10.1021/co200022uen_US
dc.identifier.urihttp://hdl.handle.net/11536/21969-
dc.description.abstractDiversity-oriented synthesis of novel benzimidazole linked indolo-benzodiazepine/quinoxaline ring systems using poly(ethylene glycol) as soluble polymer support is described. Corrunercially available 4-fluoro-3-nitrobenzoic acid and indoline were utilized for the construction of these annulated biheterocyclic compound libraries having multiple privileged structures with three-point structural diversity. A reagent based diversification approach coupled with the Pictet-Spengler-type condensation was used to construct the tetracydic indolo-benzodiazepines/quinoxalines on substituted benzimidazoles.en_US
dc.language.isoen_USen_US
dc.subjectindolo-benzodiazepines/quinoxalinesen_US
dc.subjectPictet-Spengleren_US
dc.subjectdiversity-oriented synthesisen_US
dc.subjectPEGen_US
dc.titleDivergent Synthesis of Unsymmetrical Annulated Biheterocyclic Compound Libraries: Benzimidazole Linked Indolo-benzodiazepines/quinoxalineen_US
dc.typeArticleen_US
dc.identifier.doi10.1021/co200022uen_US
dc.identifier.journalACS COMBINATORIAL SCIENCEen_US
dc.citation.volume13en_US
dc.citation.issue4en_US
dc.citation.spage391en_US
dc.citation.epage398en_US
dc.contributor.department應用化學系zh_TW
dc.contributor.departmentDepartment of Applied Chemistryen_US
dc.identifier.wosnumberWOS:000292617500007-
dc.citation.woscount11-
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