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dc.contributor.authorChang, YRen_US
dc.contributor.authorHsu, Len_US
dc.contributor.authorChi, Sen_US
dc.date.accessioned2014-12-08T15:34:55Z-
dc.date.available2014-12-08T15:34:55Z-
dc.date.issued2005-02-01en_US
dc.identifier.issn0030-4018en_US
dc.identifier.urihttp://dx.doi.org/10.1016/j.optcom.2004.10.066en_US
dc.identifier.urihttp://hdl.handle.net/11536/23743-
dc.description.abstractOptical tweezers have become a popular manipulation and force measurement tool in cellular and molecular biology. However, there is still a lack of a sophisticated model for optical tweezers on trapping cells. In this paper, we present a novel model for optical tweezers to calculate the stiffness of trapping force upon a spherically symmetric Rayleigh sphere, which stimulates a common biological cell. A numerical simulation of this model shows that the stiffness of an optical tweezers system in trapping a cell is significantly smaller than that in trapping a polystyrene bead of the same size. Furthermore, under a small variant condition of the refractive index, the proposed model provides an approximate method which requires only the radial distribution of the trapped cell's refractive index for calculating the stiffness. (C) 2004 Elsevier B.V. All rights reserved.en_US
dc.language.isoen_USen_US
dc.subjectoptical tweezersen_US
dc.subjectRayleigh scatteringen_US
dc.subjectbiophotonicsen_US
dc.titleOptical trapping of a spherically symmetric Rayleigh sphere: a model for optical tweezers upon cellsen_US
dc.typeArticleen_US
dc.identifier.doi10.1016/j.optcom.2004.10.066en_US
dc.identifier.journalOPTICS COMMUNICATIONSen_US
dc.citation.volume246en_US
dc.citation.issue1-3en_US
dc.citation.spage97en_US
dc.citation.epage105en_US
dc.contributor.department電子物理學系zh_TW
dc.contributor.department光電工程學系zh_TW
dc.contributor.departmentDepartment of Electrophysicsen_US
dc.contributor.departmentDepartment of Photonicsen_US
dc.identifier.wosnumberWOS:000226896600015-
dc.citation.woscount9-
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