標題: | Synthesis of a carboxyl linker containing P-k trisaccharide |
作者: | Hsieh, SY Jan, MD Patkar, LN Chen, CT Lin, CC 應用化學系 Department of Applied Chemistry |
關鍵字: | P-k antigen.;galactosyl phosphite;glycosylation;alpha-selectivity |
公開日期: | 17-一月-2005 |
摘要: | An efficient synthesis of a p(k) trisaccharide with a functionalized side arm at the reducing end for conjugation to other molecules is presented. Construction of the pk trisaccharide with a high alpha-selectivity was achieved in high yield by coupling a reactive galactosyl phosphite donor with a lactosyl acceptor. (C) 2004 Elsevier Ltd. All rights reserved. |
URI: | http://dx.doi.org/10.1016/j.carres.2004.10.024 http://hdl.handle.net/11536/24129 |
ISSN: | 0008-6215 |
DOI: | 10.1016/j.carres.2004.10.024 |
期刊: | CARBOHYDRATE RESEARCH |
Volume: | 340 |
Issue: | 1 |
起始頁: | 49 |
結束頁: | 57 |
顯示於類別: | 期刊論文 |