家族發病時間資料之統計推論 - 文獻回顧

Abstract

在本論文中，我們回顧有關分析家族發病時間的統計文獻。我們以統整的架構，說明如何探討變數間的關聯性，與建立聯合分佈的方法。討論也包含如何將解釋變數納入分析中的方法。在介紹完模式之理論意義與性質之後，我們討論幾個文獻的實例，了解統計推論所牽涉到的問題與解決的方法。

In the thesis, we review literature on statistical analysis of familial age-onset data. A unified framework is provided to illustrate how statistical methods are applied to investigate interesting scientific phenomenon. We discuss some important association measures and several approaches to handling correlated failure time variables. The extension to include the effect of covariates is also introduced. Finally we discuss applications of these theoretical models to biomedical data.