后馬託品全合成之研究

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DC Field	Value	Language
dc.contributor.author	許良榮	en_US
dc.contributor.author	Xu, Liang-Rong	en_US
dc.contributor.author	莊祚敏	en_US
dc.contributor.author	Zhuang, Zuo-Min	en_US
dc.date.accessioned	2014-12-12T02:04:03Z	-
dc.date.available	2014-12-12T02:04:03Z	-
dc.date.issued	1985	en_US
dc.identifier.uri	http://140.113.39.130/cdrfb3/record/nctu/#NT744500001	en_US
dc.identifier.uri	http://hdl.handle.net/11536/52704	-
dc.description.abstract	利用ROBINSON-SCHOPF 反應，以□喃（FURAN ）為起始物，製備託品酮（TROPINONE ）１０後，經由立體選擇性之還原合成託品（TROPINE ）３，再與由苹甲醛（BENZAL DEHYDE）經修飾STRECKER方法所製備之苯乙胺酸（PHENYLGLYCIN）８進行脫氨基反應（DEAMINATION ）所合成之扁桃酸（HOMATROPINE ）２進行酯化，而完成后馬託品（ HOMATROPINE ）LE之合成，並製成藥用的后馬託品氫溴酸鹽（HOMATROPINE HYDROBRO MIDE）２６。並由后馬託品之全合成，提供具類似結構之藥物，如東莨菪鹼（（一）SCOPOLAMINE ）LA，曼陀羅素（（一）HYOSCYAMINE ）LB之成訊息及可能模式。	zh_TW
dc.language.iso	zh_TW	en_US
dc.subject	后馬託品	zh_TW
dc.subject	全合成	zh_TW
dc.subject	合成	zh_TW
dc.subject	託品	zh_TW
dc.subject	□喃	zh_TW
dc.subject	託品酮	zh_TW
dc.subject	應用化學	zh_TW
dc.subject	化學	zh_TW
dc.subject	HOMATROPINE	en_US
dc.subject	TROPINE	en_US
dc.subject	APPLIED-CHEMISTRY	en_US
dc.subject	CHEMISTRY	en_US
dc.title	后馬託品全合成之研究	zh_TW
dc.title	The total synthesis of Homatropine	en_US
dc.type	Thesis	en_US
dc.contributor.department	應用化學系碩博士班	zh_TW
Appears in Collections:	Thesis