標題: | Transparent microprobe array fabricated by MEMS hot embossing technology for photodynamic therapy application |
作者: | Hung, Chen-Chun Chiou, Jin-Chern Chang, Chih-Wei 電控工程研究所 Institute of Electrical and Control Engineering |
關鍵字: | MEMS;photodynamic therapy;needle array;hot embossing |
公開日期: | 10-五月-2010 |
摘要: | This work describes a novel transparent micro-needle array for photodynamic therapy (PDT) applications. This micro-needle array, with 250 um in height and 35 um in diameter, was placed onto skin and penetrated the cuticle yet not reaching the corium layer, so as to avoid pain and bleeding but achieve superior light transmission efficiency. For PDT applications, this design can significantly reduce the required incident power and therefore avoid additional damage to surrounding healthy tissue. Practical in-vivo test on human skin demonstrates the improved power transmission efficiency (PTE) of two types of needle arrays is 1.41 and 1.71 times better than the condition without using micro-needle array. |
URI: | http://dx.doi.org/10.1587/elex.7.569 http://hdl.handle.net/11536/5410 |
ISSN: | 1349-2543 |
DOI: | 10.1587/elex.7.569 |
期刊: | IEICE ELECTRONICS EXPRESS |
Volume: | 7 |
Issue: | 9 |
起始頁: | 569 |
結束頁: | 576 |
顯示於類別: | 期刊論文 |