製備金奈米線和聚吡咯之核殼結構於可撓式基材及其在分子模板之電化學感測應用

Abstract

分子模板是利用高分子為骨架來提供人造受體的技術。此人造受體可做為目標分子的辨識與萃取工具。在本篇研究中使用直流電源供應器以電化學沉積法在可撓式基材上合成金奈米線，之後在三電極系統中利用循環伏安法製備金奈米線以及聚吡咯之核殼結構作為分子模板的電化學偵測器來感測多巴胺。在合成過程中，利用循環伏安法的掃描速率來將合成條件最佳化並使用差式脈波伏安法來偵測多巴胺濃度。金奈米線/聚吡咯核殼結構電極在多巴胺的偵測上表現出良好的靈敏度(805 A mM-1) 以及其偵測範圍為4 x 10-7 – 1 x 10-5 mol L-1 (N=3).

Molecular imprinting is a technique for preparing polymer scaffolds that function as synthetic receptors. These receptors have significant signal intensity difference between the binding and the extraction of the target molecules. In this work, we fabricated gold-nanowires (Au NWs) on flexible substrates by direct current electrochemical deposition. Then, we electropolymerized a polypyrrole layer onto the Au NWs via cyclic voltammetry (CV) as the molecular imprinted polymer biosensor to detect dopamine (DA). The influence of the scan rate of CV for the sensor preparation was optimized. CV and differential pulse voltammetry (DPV) were used to measurement different DA concentrations. The Au/polypyrrole core/shell nanowires sensor showed good DPV signal intensity at 805 A mM-1 and the determined linear range for DA was 4 x 10-7 – 1 x 10-5 mol L-1 (N=3).