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dc.contributor.authorJhan, Jhen-Weien_US
dc.contributor.authorChang, Wei-Tienen_US
dc.contributor.authorChen, Hung-Cheen_US
dc.contributor.authorLee, Yu-Tsungen_US
dc.contributor.authorWu, Ming-Fangen_US
dc.contributor.authorChen, Chung-Hsuanen_US
dc.contributor.authorLiau, Ianen_US
dc.date.accessioned2014-12-08T15:10:47Z-
dc.date.available2014-12-08T15:10:47Z-
dc.date.issued2008-10-13en_US
dc.identifier.issn1094-4087en_US
dc.identifier.urihttp://dx.doi.org/10.1364/OE.16.016431en_US
dc.identifier.urihttp://hdl.handle.net/11536/8253-
dc.description.abstractHistopathological imaging of tissues often requires extensive sample preparation including fixation and staining in order to highlight characteristic alterations associated with diseases. Herein, we report an integrated spectro-microscopy approach based on a combination of multimodal multi-photon imaging and Raman micro-spectroscopy and demonstrate label-free characterization of the structure-constituent correlation of porcine skin. The multi-modal imaging allows the visualization of dermatological features whereas Raman micro-spectroscopy enables the identification of their 'molecular fingerprints'. By obtaining both structural and molecular-level information of tissue constituents, this integrated approach can offer new insight into the patho-physiological status of tissues. (c) 2008 Optical Society of Americaen_US
dc.language.isoen_USen_US
dc.titleIntegrated multiple multi-photon imaging and Raman spectroscopy for characterizing structure-constituent correlation of tissuesen_US
dc.typeArticleen_US
dc.identifier.doi10.1364/OE.16.016431en_US
dc.identifier.journalOPTICS EXPRESSen_US
dc.citation.volume16en_US
dc.citation.issue21en_US
dc.citation.spage16431en_US
dc.citation.epage16441en_US
dc.contributor.department應用化學系zh_TW
dc.contributor.department應用化學系分子科學碩博班zh_TW
dc.contributor.departmentDepartment of Applied Chemistryen_US
dc.contributor.departmentInstitute of Molecular scienceen_US
dc.identifier.wosnumberWOS:000260864900016-
dc.citation.woscount15-
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