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dc.contributor.authorKalkhambkar, Rajesh G.en_US
dc.contributor.authorKulkarni, Geeta M.en_US
dc.contributor.authorKamanavalli, Chandrappa M.en_US
dc.contributor.authorPremkumar, N.en_US
dc.contributor.authorAsdaq, S. M. B.en_US
dc.contributor.authorSun, Chung Mingen_US
dc.date.accessioned2014-12-08T15:10:50Z-
dc.date.available2014-12-08T15:10:50Z-
dc.date.issued2008-10-01en_US
dc.identifier.issn0223-5234en_US
dc.identifier.urihttp://dx.doi.org/10.1016/j.ejmech.2007.08.007en_US
dc.identifier.urihttp://hdl.handle.net/11536/8287-
dc.description.abstractA series of new fluorinated coumarins and 1-aza coumarins have been synthesized and the presence of fluorine in these molecules and its effect on their anti-microbial, anti-inflammatory and analgesic activities are discussed. The results of bioassay showed that these newly synthesized compounds containing fluorine exhibit moderate analgesic and excellent anti-inflammatory and potential anti-bacterial and anti-fungal activities, compared to the other halogenated compounds. All the newly synthesized compounds were characterized by elemental analysis, IR, (1)H NMR, (13)C NMR, (19)F NMR, EI-MS, and FAB-MS. The ORTEP diagram of one of the compounds is reported herein. (C) 2007 Elsevier Masson SAS. All rights reserved.en_US
dc.language.isoen_USen_US
dc.subjectFluorinated coumarinen_US
dc.subjectFluorinated 1-aza coumarinen_US
dc.subjectAnti-bacterialen_US
dc.subjectAnti-fungalen_US
dc.subjectAnalgesicen_US
dc.subjectAnti-inflammatoryen_US
dc.titleSynthesis and biological activities of some new fluorinated coumarins and 1-aza coumarinsen_US
dc.typeArticleen_US
dc.identifier.doi10.1016/j.ejmech.2007.08.007en_US
dc.identifier.journalEUROPEAN JOURNAL OF MEDICINAL CHEMISTRYen_US
dc.citation.volume43en_US
dc.citation.issue10en_US
dc.citation.spage2178en_US
dc.citation.epage2188en_US
dc.contributor.department應用化學系zh_TW
dc.contributor.departmentDepartment of Applied Chemistryen_US
dc.identifier.wosnumberWOS:000260898800015-
dc.citation.woscount32-
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