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dc.contributor.authorChen, Hsia-Yuanen_US
dc.contributor.authorKulkarni, Manohar V.en_US
dc.contributor.authorChen, Chih-Hauen_US
dc.contributor.authorSun, Chung-Mingen_US
dc.date.accessioned2014-12-08T15:11:20Z-
dc.date.available2014-12-08T15:11:20Z-
dc.date.issued2008-06-30en_US
dc.identifier.issn0040-4020en_US
dc.identifier.urihttp://dx.doi.org/10.1016/j.tet.2008.04.081en_US
dc.identifier.urihttp://hdl.handle.net/11536/8694-
dc.description.abstractChemical stability and reactivity of a bifunctional polymer conjugate containing an ortho-amino arylamide linkage have been successfully exploited to achieve a parallel synthesis of methoxycarbonylated head-tail bis-benzimidazoles. Regioselective alkylation of the two nitrogens in the benzimidazolone moiety has been carried out by ipso-fluoro displacement, and N-alkylation to generate two diversities. Cleavage of the polymer support has resulted in two libraries of di- and tri-substituted benzimidazolyl benzimidazolones in high purity and high yield. All reaction steps have been monitored by (1)H NMR on the support directly. (c) 2008 Elsevier Ltd. All rights reserved.en_US
dc.language.isoen_USen_US
dc.titleSynthesis of structurally diverse benzimidazolyl benzimidazolones by application of soluble polymer supporten_US
dc.typeArticleen_US
dc.identifier.doi10.1016/j.tet.2008.04.081en_US
dc.identifier.journalTETRAHEDRONen_US
dc.citation.volume64en_US
dc.citation.issue27en_US
dc.citation.spage6387en_US
dc.citation.epage6394en_US
dc.contributor.department應用化學系zh_TW
dc.contributor.departmentDepartment of Applied Chemistryen_US
dc.identifier.wosnumberWOS:000256895100029-
dc.citation.woscount7-
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