Regioselective One-Pot Protection of D-Glucosamine

Abstract

A highly regioselective one-pot transformation of 2-azido2-deoxy-1,3,4,6-tetra-O-trimethylsilyl-D-glucopyranose via sequential additions of various reagents was systematically studied, yielding the fully protected derivatives and the 1-, 3-, 4-, as well as 6-alcohols, respectively.