標題: | NANOPARTICLE AND MAGNETIC RESONANCE IMAGING CONTRAST AGENT |
作者: | Wang, Yun-Ming Chen, Ting-Jung |
公開日期: | 21-四月-2011 |
摘要: | A nanoparticle contains a core including superparamagnetic nanoparticles and having an outer surface, and siloxanyl moieties covalently coupled to the outer surface of the core and having Formula (I):In formula (I): X1 and X2 independently represent methylene, ethylene or propylene; R represents an optionally substituted pyridyl group, or —S—R is a group derived from a targeting ligand containing —SH group and effective to bind specifically with a predetermined targeted cell in an object; n and m independently represent an integer ranging from 1 to 3; and p represents an integer ranging from 9 to 45. The nanoparticles are suitable for use as a magnetic resonance imaging contrast agent. |
官方說明文件#: | C07F007/18 C07K007/06 C07K014/54 |
URI: | http://hdl.handle.net/11536/105309 |
專利國: | USA |
專利號碼: | 20110092672 |
顯示於類別: | 專利資料 |