標題: | Ritter reaction of 1-aryl-1-fluoro-2-haloethanes |
作者: | Ho, TL Chein, RJ 應用化學系 Department of Applied Chemistry |
關鍵字: | Ritter reaction;4,5-dihydrooxazole |
公開日期: | 1-Apr-2006 |
摘要: | Fluorinated phenethyl bromides 1, 2, and 3, prove to be totally inert under Ritter reaction conditions in the presence of either SnCl4 or AgNO3, due to the strong deactivation by the gem-difluoro unit. Subjecting 2-bromo-1-fluoro-1-phenylethane to SnCl4 in MeCN at elevated temperatures led to formation of 2-methyl-4-phenyl-4,5-dihydrooxazole. |
URI: | http://hdl.handle.net/11536/12452 |
ISSN: | 0009-4536 |
期刊: | JOURNAL OF THE CHINESE CHEMICAL SOCIETY |
Volume: | 53 |
Issue: | 2 |
起始頁: | 429 |
結束頁: | 430 |
Appears in Collections: | Articles |