標題: A cost-effective fabrication of iridium oxide films as biocompatible electrostimulation electrodes for neural interface applications
作者: Chen, Yong-Min
Chung, Tsai-Wei
Wu, Pu-Wei
Chen, Po-Chun
材料科學與工程學系
Department of Materials Science and Engineering
關鍵字: Neurostimulation;Bio-interface;Biocompatible electrostimulation electrode;Iridium oxide;Chemical bath deposition
公開日期: 25-Jan-2017
摘要: Electrostimulation medical devices for neural diseases require electroactive and biocompatible interface materials to transmit signals from electrodes to targeting tissues. Iridium oxide is an attractive ceramic material for neurostimulation electrodes due to its desirable stability and biocompatibility. In this study, we developed a cost effective and thickness controllable process to fabricate iridium oxide film by chemical bath deposition (CIROF). Surface morphology, crystallinity, roughness, hydrophilicity, and charge storage capacity as well as biocompatibility of the CIROFs with different thicknesses were analyzed. Accordingly, the CIROFs present rough and hydrophilic surfaces for cell attachment and good biocompatibility for cell viability. In addition, the charge storage capacity (CSC) of the as-deposited and the annealed CIROFs were 78.29 mC/cm(2) and 71.76 mC/cm(2), respectively. Consequently, these results show advantages that make the CIROF a promising neurostimulation electrode material for implantable medical devices in neural systems. (C) 2016 Elsevier B.V. All rights reserved.
URI: http://dx.doi.org/10.1016/j.jallcom.2016.09.064
http://hdl.handle.net/11536/132593
ISSN: 0925-8388
DOI: 10.1016/j.jallcom.2016.09.064
期刊: JOURNAL OF ALLOYS AND COMPOUNDS
Volume: 692
起始頁: 339
結束頁: 345
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