標題: Using Innovative Acoustic Analysis to Predict the Postoperative Outcomes of Unilateral Vocal Fold Paralysis
作者: Tsou, Yung-An
Liu, Yi-Wen
Chang, Wen-Dien
Chen, Wei-Chen
Ke, Hsiang-Chun
Lin, Wen-Yang
Yang, Hsing-Rong
Shie, Dung-Yun
Tsai, Ming-Hsui
生物科技學系
Department of Biological Science and Technology
公開日期: 1-一月-2016
摘要: Objective. Autologous fat injection laryngoplasty is ineffective for some patients with iatrogenic vocal fold paralysis, and additional laryngeal framework surgery is often required. An acoustically measurable outcome predictor for lipoinjection laryngoplasty would assist phonosurgeons in formulating treatment strategies. Methods. Seventeen thyroid surgery patients with unilateral vocal fold paralysis participated in this study. All subjects underwent lipoinjection laryngoplasty to treat postsurgery vocal hoarseness. After treatment, patients were assigned to success and failure groups on the basis of voice improvement. Linear prediction analysis was used to construct a new voice quality indicator, the number of irregular peaks (NIrrP). It compared with the measures used in the Multi-Dimensional Voice Program(MDVP), such as jitter (frequency perturbation) and shimmer (perturbation of amplitude). Results. By comparing the [i] vowel produced by patients before the lipoinjection laryngoplasty (AUC = 0.98, 95% CI = 0.78-0.99), NIrrP was shown to be a more accurate predictor of long-term surgical outcomes than jitter (AUC = 0.73, 95% CI = 0.47-0.91) and shimmer (AUC = 0.63, 95% CI = 0.37-0.85), as identified by the receiver operating characteristic curve. Conclusions. NIrrP measured using the LP model could be a more accurate outcome predictor than the parameters used in the MDVP.
URI: http://dx.doi.org/10.1155/2016/7821415
http://hdl.handle.net/11536/132705
ISSN: 2314-6133
DOI: 10.1155/2016/7821415
期刊: BIOMED RESEARCH INTERNATIONAL
起始頁: 0
結束頁: 0
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