標題: Chiral liquid crystals as biosensing platforms
作者: Lee, Mon-Juan
Sung, Yu-Chien
Hsiao, Yu-Cheng
Lee, Wei
影像與生醫光電研究所
Institute of Imaging and Biomedical Photonics
關鍵字: Liquid crystals;Cholesteric liquid crystals;Transmission spectroscopy;Biophotonics;Biosensors
公開日期: 1-Jan-2016
摘要: The texture observation has long been the core technique in liquid crystal (LC)-based bioassays. Its working principle stems from the dark-to-bright texture change induced by the interruption of the initially homeotropic alignment in nematic bulks or from the radial-to-bipolar configuration transition in LC droplets in the presence of biomolecules. One of the drawbacks of this observational scheme, which requires a polarizing optical microscope, is the difficulty in quantitative analysis. In this invited paper, we report on our recent development of alternative optical biosensing techniques based on cholesteric LCs (CLCs) without the use of a polarizer. The increase in structural order in a vertically anchored CLC cell in the quasi-planar state provides a means to allow detection and quantification of the concentration of biomolecules immobilized on the interface between the mesophase and the surfactant DMOAP for LC vertical alignment.
URI: http://dx.doi.org/10.1117/12.2236774
http://hdl.handle.net/11536/136393
ISBN: 978-1-5106-0271-7; 978-1-5106-0272-4
ISSN: 0277-786X
DOI: 10.1117/12.2236774
期刊: LIQUID CRYSTALS XX
Volume: 9940
起始頁: 0
結束頁: 0
Appears in Collections:Conferences Paper


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