以近紅外光譜技術量測纖維肌痛症訊號之研究

Abstract

纖維肌痛症隨著年齡的增長，也有穩定增加的趨勢，纖維肌痛症其實並不少見，但由於病症的複雜，往往造成診斷上的困難，雖無法完全根治，但只要我們試著去瞭解，以及接受醫生的治療，就能獲得改善，因此我們需要一種適合長期監測病患情況的儀器，並希望未來能夠協助醫生進行診斷，提供更好的醫療環境。 本篇論文撰寫目的以近紅外光譜技術量測纖維肌痛受試者前額葉在閉氣實驗後血管反應性，並發現與正常受試者有著不同差異，此外血管束縛實驗初步證實了纖維肌痛症受試者與正常受試者骨骼肌肉回復程度的差別，我們希望此兩種量測方法跟技術能隨著需求更加成熟，而為其他心血管相關慢性病，提供更精確的資料統計和判讀。

Fibromyalgia syndrome (FMS) is a common chronic condition characterized by persistent, widespread musculoskeletal pain and diffuse tenderness at multiple tender points. According to statistics, approximately every one hundred adults, there were two patients with fibromyalgia, a slightly higher incidence of women than men. Some researches found that patients with fibromyalgia brain structure and neural networks may be altered by the persistent pain and relationship between prefrontal and temporal lobe may be a target differentiate from the neurologic disorders. This thesis of the purpose is measuring prefrontal blood oxygen signal representative of whether there would be differences in vascular reactivity by NIRS performing breathe-holding task between patients onset fibromyalgia and healthy controls, and confirmed the differences in skeletal muscle recovery responses between two groups. We hope to provide doctors more accurate statistics and interpretation in diagnosis.