標題: Coumarin-based Hg2+ fluorescent probe: Fluorescence turn-on detection for Hg2+ bioimaging in living cells and zebrafish
作者: Chen, Chong-Guang
Vijay, Natarajan
Thirumalaivasan, Natesan
Velmathi, Sivan
Wu, Shu-Pao
應用化學系
Department of Applied Chemistry
關鍵字: Hg(II);Sensor;Coumarin;Bioimaging;Zebrafish
公開日期: 5-Aug-2019
摘要: The need in developing fluorescent probes for trace metal ion detection in biological samples has been an important issue. Herein, a reaction-based fluorescent probe PIC containing a perimidine moiety was designed and synthesized for Hg2+ detection. The probe can selectively distinguish Hg2+ with 42-fold fluorescent enhancement from the other metal ions at physiological pH. This probe can detect Hg2+ with the detection limit of 1.08 mu M. The sensor PIC can be applied to real-time detection of Hg2+ in cells with blue emission. (C) 2019 Elsevier B.V. All rights reserved.
URI: http://dx.doi.org/10.1016/j.saa.2019.04.048
http://hdl.handle.net/11536/152174
ISSN: 1386-1425
DOI: 10.1016/j.saa.2019.04.048
期刊: SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
Volume: 219
起始頁: 135
結束頁: 140
Appears in Collections:Articles