標題: An Inkjet-Printed Flexible Non-Enzymatic Lactate Sensor for Clinical Blood Plasma Test
作者: Huang, Yi-Syuan
Chen, Kuan-Yu
Cheng, Yu-Ting
Lee, Chih-Kuo
Tsai, Hsiao-En
交大名義發表
National Chiao Tung University
關鍵字: Inkjet printing;non-enzyme;lactate sensors;blood test
公開日期: 1-四月-2020
摘要: In this letter, we demonstrate a fully inkjet-printed electrochemical lactate sensor. The sensor is inkjet-printed on a flexible substrate, Kapton film, where silver nanoparticles (Ag NPs) are printed as conductive electrodes. The working and reference electrodes of the sensor are Ag NPs/NiO NPs/Polyurethane (PU) and Ag/AgCl(s)/PU layers respectively. The inkjet-printed PU film can not only prevent the annihilation of the Ag NPs resulting from the dissolution of Ag and the formation of AgCl in the phosphate-buffered saline (PBS) but also stabilize the lactic acid measurements by maintaining a potential variant within 2% at different lactate concentrations. The as-printed sensor exhibits a linear sensitivity of 8.86nA/mM/mm(2) (R=99.6%) in the range from 0.6 to 2.2 mM. Clinical blood plasma testing results show that the trends of lactic acid change in patients measured by the sensor are the same as the ones measured using the existing detection method, colorimetric assays, in a tertiary university-affiliated hospital.
URI: http://dx.doi.org/10.1109/LED.2020.2973343
http://hdl.handle.net/11536/154237
ISSN: 0741-3106
DOI: 10.1109/LED.2020.2973343
期刊: IEEE ELECTRON DEVICE LETTERS
Volume: 41
Issue: 4
起始頁: 597
結束頁: 600
顯示於類別:期刊論文