完整後設資料紀錄
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Chen, Wei-Ming | en_US |
dc.contributor.author | Chiueh, Herming | en_US |
dc.contributor.author | Chen, Tsan-Jieh | en_US |
dc.contributor.author | Ho, Chia-Lun | en_US |
dc.contributor.author | Jeng, Chi | en_US |
dc.contributor.author | Ker, Ming-Dou | en_US |
dc.contributor.author | Lin, Chun-Yu | en_US |
dc.contributor.author | Huang, Ya-Chun | en_US |
dc.contributor.author | Chou, Chia-Wei | en_US |
dc.contributor.author | Fan, Tsun-Yuan | en_US |
dc.contributor.author | Cheng, Ming-Seng | en_US |
dc.contributor.author | Hsin, Yue-Loong | en_US |
dc.contributor.author | Liang, Sheng-Fu | en_US |
dc.contributor.author | Wang, Yu-Lin | en_US |
dc.contributor.author | Shaw, Fu-Zen | en_US |
dc.contributor.author | Huang, Yu-Hsing | en_US |
dc.contributor.author | Yang, Chia-Hsiang | en_US |
dc.contributor.author | Wu, Chung-Yu | en_US |
dc.date.accessioned | 2014-12-08T15:33:56Z | - |
dc.date.available | 2014-12-08T15:33:56Z | - |
dc.date.issued | 2014-01-01 | en_US |
dc.identifier.issn | 0018-9200 | en_US |
dc.identifier.uri | http://dx.doi.org/10.1109/JSSC.2013.2284346 | en_US |
dc.identifier.uri | http://hdl.handle.net/11536/23387 | - |
dc.description.abstract | An 8-channel closed-loop neural-prosthetic SoC is presented for real-time intracranial EEG (iEEG) acquisition, seizure detection, and electrical stimulation in order to suppress epileptic seizures. The SoC is composed of eight energy-efficient analog front-end amplifiers (AFEAs), a 10-b delta-modulated SAR ADC (DMSAR ADC), a configurable bio-signal processor (BSP), and an adaptive high-voltage-tolerant stimulator. A wire-less power-and-data transmission system is also embedded. By leveraging T-connected pseudo-resistors, the high-pass (low-pass) cutoff frequency of the AFEAs can be adjusted from 0.1 to 10 Hz (0.8 to 7 kHz). The noise-efficiency factor (NEF) of the AFEA is 1.77, and the DMSAR ADC achieves an ENOB of 9.57 bits. The BSP extracts the epileptic features from time-domain entropy and frequency spectrum for seizure detection. A constant 30-mu A stimulus current is delivered by closed-loop control. The acquired signals are transmitted with on-off keying (OOK) modulation at 4 Mbps over the MedRadio band for monitoring. A multi-LDO topology is adopted to mitigate the interferences across different power domains. The proposed SoC is fabricated in 0.18-mu m CMOS and occupies 13.47 mm(2). Verified on Long Evans rats, the proposed SoC dissipates 2.8 mW and achieves high detection accuracy 92% within 0.8 s. | en_US |
dc.language.iso | en_US | en_US |
dc.subject | Closed-loop control | en_US |
dc.subject | epilepsy | en_US |
dc.subject | neuron modulation | en_US |
dc.subject | neural prosthesis | en_US |
dc.subject | system-on-Chip (SoC) | en_US |
dc.subject | wireless power transmission | en_US |
dc.title | A Fully Integrated 8-Channel Closed-Loop Neural-Prosthetic CMOS SoC for Real-Time Epileptic Seizure Control | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.1109/JSSC.2013.2284346 | en_US |
dc.identifier.journal | IEEE JOURNAL OF SOLID-STATE CIRCUITS | en_US |
dc.citation.volume | 49 | en_US |
dc.citation.issue | 1 | en_US |
dc.citation.spage | 232 | en_US |
dc.citation.epage | 247 | en_US |
dc.contributor.department | 電機資訊學士班 | zh_TW |
dc.contributor.department | 電子工程學系及電子研究所 | zh_TW |
dc.contributor.department | 生醫電子轉譯研究中心 | zh_TW |
dc.contributor.department | Undergraduate Honors Program of Electrical Engineering and Computer Science | en_US |
dc.contributor.department | Department of Electronics Engineering and Institute of Electronics | en_US |
dc.contributor.department | Biomedical Electronics Translational Research Center | en_US |
dc.identifier.wosnumber | WOS:000329052700022 | - |
dc.citation.woscount | 3 | - |
顯示於類別: | 期刊論文 |