标题: | Directly Thiolated Modification onto the Surface of Detonation Nanodiamonds |
作者: | Hsu, Ming-Hua Chuang, Hong Cheng, Fong-Yu Huang, Ying-Pei Han, Chien-Chung Chen, Jiun-Yu Huang, Su-Chin Chen, Jen-Kun Wu, Dian-Syue Chu, Hsueh-Liang Chang, Chia-Ching 生物科技学系 Department of Biological Science and Technology |
关键字: | thiolated;nanodiamond;detonation nanodiamond;surface modification;thiolated nanodiamond;functionalized nanodiamond |
公开日期: | 28-五月-2014 |
摘要: | An efficient method for modifying the surface of detonation nanodiamonds (5 and 100 nm) with thiol groups (-SH) by using an organic chemistry strategy is presented herein. Thiolated nanodiamonds were characterized by spectroscopic techniques, and the atomic percentage of sulfur was analyzed by elemental analysis and X-ray photoelectron spectroscopy. The conjugation between thiolated nanodiamonds and gold nanoparticles was elucidated by transmission electron microscopy and UV-vis spectrometry. Moreover, the material did not show significant cytotoxicity to the human lung carcinoma cell line and may prospectively be applied in bioconjugated technology. The new method that we elucidated may significantly improve the approach to surface modification of detonation nanodiamonds and build up a new platform for the application of nanodiamonds. |
URI: | http://dx.doi.org/10.1021/am500324z http://hdl.handle.net/11536/24417 |
ISSN: | 1944-8244 |
DOI: | 10.1021/am500324z |
期刊: | ACS APPLIED MATERIALS & INTERFACES |
Volume: | 6 |
Issue: | 10 |
起始页: | 7198 |
结束页: | 7203 |
显示于类别: | Articles |
文件中的档案:
If it is a zip file, please download the file and unzip it, then open index.html in a browser to view the full text content.