Spectroscopic study of bio-functionalized nanodiamonds

Title:	Spectroscopic study of bio-functionalized nanodiamonds
Authors:	Chung, P. -H. Perevedentseva, E. Tu, J. -S. Chang, C. C. Cheng, C. -L. 生物科技學系 Department of Biological Science and Technology
Keywords:	nanodiamonds;biomedical applications;sensors;surface characterization
Issue Date:	1-Apr-2006
Abstract:	Nano-scale materials with attached biomolecules on the surface can be used as bioprobes in cell and tissue analysis. The conjugation of these nanoparticles with biomolecules is one of the key steps in the development of bioprobes. In this work nanometer-sized diamonds (5 and 100 nm) are functionalized and conjugated with protein lysozyme via physical adsorption. The process of creating functional groups on the nanodiamond surface is studied using Fourier Transform Infrared-spectroscopy (FTIR). The conjugation of nanodiamonds with biontolecules and nanodiamond-biomolecule interaction are analyzed with UV/VIS and FTIR spectroscopy. (c) 2005 Elsevier B.V. All rights reserved.
URI:	http://dx.doi.org/10.1016/j.diamond.2005.11.019 http://hdl.handle.net/11536/12439
ISSN:	0925-9635
DOI:	10.1016/j.diamond.2005.11.019
Journal:	DIAMOND AND RELATED MATERIALS
Volume:	15
Issue:	4-8
Begin Page:	622
End Page:	625
Appears in Collections:	Conferences Paper

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