Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lu, U | en_US |
dc.contributor.author | Hu, BCP | en_US |
dc.contributor.author | Shih, YC | en_US |
dc.contributor.author | Wu, CY | en_US |
dc.contributor.author | Yang, YS | en_US |
dc.date.accessioned | 2014-12-08T15:39:10Z | - |
dc.date.available | 2014-12-08T15:39:10Z | - |
dc.date.issued | 2004-05-15 | en_US |
dc.identifier.issn | 0956-5663 | en_US |
dc.identifier.uri | http://dx.doi.org/10.1016/j.bios.2003.11.025 | en_US |
dc.identifier.uri | http://hdl.handle.net/11536/26772 | - |
dc.description.abstract | We designed a complementary metal oxide semiconductor (CMOS) chip with accompanied accessories as a system for the detections and quantifications of biochemical luminescence. This is the first of such instruments that has been reported. The semiconductor chip was manufactured through a 0.25 mum CMOS standard process. A current mirror was designed in integrated circuit (IC) to amplify the signal current that was induced by chemiluminescence. Horseradish peroxidase (HRP)-luminol-H2O2 system was used as an example to constitute a useful platform for coupling to chemiluminescence reactions which produce H2O2. Glucose-glucose oxidase (GOD) reaction was coupled with HRP-luminol-H2O2 reaction to demonstrate the ability of the novel CMOS base instrument for quantifying the biological luminescence of a variety of valuable clinical assays. Our results illustrated that the combination of the specifically designed CMOS IC and commercially available electronic devices established a simple and useful bioanalytical tool. (C) 2003 Elsevier B.V. All rights reserved. | en_US |
dc.language.iso | en_US | en_US |
dc.subject | CMOS | en_US |
dc.subject | IC design | en_US |
dc.subject | bioluminescence | en_US |
dc.subject | enzyme chip | en_US |
dc.subject | biochemical analysis | en_US |
dc.title | The design of a novel complementary metal oxide semiconductor detection system for biochemical luminescence | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.1016/j.bios.2003.11.025 | en_US |
dc.identifier.journal | BIOSENSORS & BIOELECTRONICS | en_US |
dc.citation.volume | 19 | en_US |
dc.citation.issue | 10 | en_US |
dc.citation.spage | 1185 | en_US |
dc.citation.epage | 1191 | en_US |
dc.contributor.department | 生物科技學系 | zh_TW |
dc.contributor.department | 電子工程學系及電子研究所 | zh_TW |
dc.contributor.department | Department of Biological Science and Technology | en_US |
dc.contributor.department | Department of Electronics Engineering and Institute of Electronics | en_US |
dc.identifier.wosnumber | WOS:000220702600007 | - |
dc.citation.woscount | 18 | - |
Appears in Collections: | Articles |
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