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dc.contributor.author許良榮en_US
dc.contributor.authorXU, LIANG-RONGen_US
dc.contributor.author莊祚敏en_US
dc.contributor.authorZHUANG, ZUO-MINen_US
dc.date.accessioned2014-12-12T02:03:56Z-
dc.date.available2014-12-12T02:03:56Z-
dc.date.issued1985en_US
dc.identifier.urihttp://140.113.39.130/cdrfb3/record/nctu/#NT742500003en_US
dc.identifier.urihttp://hdl.handle.net/11536/52618-
dc.description.abstract利用ROBINSON-SCHOPF 反應,以□喃(FURAN )為起始物,製備託品酮(TROPINONE )10後,經由立體選擇性之還原合成託品(TROPINE )3,再與由苹甲醛(BENZAL DEHYDE)經修飾STRECKER方法所製備之苯乙胺酸(PHENYLGLYCIN)8進行脫氨基反應 (DEAMINATION )所合成之扁桃酸(HOMATROPINE )2進行酯化,而完成后馬託品( HOMATROPINE )LE之合成,並製成藥用的后馬託品氫溴酸鹽(HOMATROPINE HYDROBRO MIDE)26。 並由后馬託品之全合成,提供具類似結構之藥物,如東莨菪鹼((一)SCOPOLAMINE )LA,曼陀羅素((一)HYOSCYAMINE )LB之成訊息及可能模式。zh_TW
dc.language.isozh_TWen_US
dc.subject后馬託品zh_TW
dc.subject全合成zh_TW
dc.subject合成zh_TW
dc.subject託品zh_TW
dc.subject□喃zh_TW
dc.subject託品酮zh_TW
dc.subjectHOMATROPINEen_US
dc.subjectTROPINEen_US
dc.title后馬託品全合成之研究zh_TW
dc.typeThesisen_US
dc.contributor.department應用化學系碩博士班zh_TW
Appears in Collections:Thesis