标题: | Patterned Poly(2-hydroxyethyl methacrylate) Brushes on Silicon Surfaces Behave as "Tentacles" To Capture Ferritin from Aqueous Solution |
作者: | Chen, Jem-Kun Chen, Zong-Yan Lin, Han-Ching Hong, Po-Da Chang, Feng-Chih 应用化学系 Department of Applied Chemistry |
关键字: | patterned PHEMA brush;VLSI process;ferritin |
公开日期: | 1-七月-2009 |
摘要: | We have used a very large scale integration process to generate well-defined patterns of polymerized 2-hydroxyethyl methacrylate (HEMA) on patterned Si(100) surfaces. An atom transfer radical polymerization initiator covalently bonded to the patterned surface was employed for the graft polymerization of HEMA to prepare the poly(2-hydroxyethyl methacrylate) (PHEMA) brushes, After immersing wafers presenting lines of these polymers in water and cyclohexane, we observed brush- and mushroom-like regions, respectively. for the PHEMA brushes, with various pattern resolutions. The PHEMA brushes behaved as "tentacles" that captured ferritin complexes from aqueous solution through entanglement between the brushes and the Ferritin proteins, whose ferritins were trapped due to the collapsing of the PHEMA. Using high-resolution scanning electron microscopy, we observed patterned ferritin iron cores on the Si surface after thermal removal of the patterned PHEMA brushes and ferritin protein sheaths. |
URI: | http://dx.doi.org/10.1021/am900190c http://hdl.handle.net/11536/7069 |
ISSN: | 1944-8244 |
DOI: | 10.1021/am900190c |
期刊: | ACS APPLIED MATERIALS & INTERFACES |
Volume: | 1 |
Issue: | 7 |
起始页: | 1525 |
结束页: | 1532 |
显示于类别: | Articles |
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