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dc.contributor.authorLiu, Xin-Ruien_US
dc.contributor.authorHsiao, Tien-Yuen_US
dc.contributor.authorLi, Yun-Qianen_US
dc.contributor.authorChiu, Kai-Shihen_US
dc.contributor.authorHuang, Chun-Jungen_US
dc.contributor.authorLi, Shan-Jien_US
dc.contributor.authorLin, Ching Poen_US
dc.contributor.authorZhao, Gangen_US
dc.contributor.authorSun, Chia-Weien_US
dc.date.accessioned2020-02-02T23:54:25Z-
dc.date.available2020-02-02T23:54:25Z-
dc.date.issued2020-01-01en_US
dc.identifier.issn1864-063Xen_US
dc.identifier.urihttp://dx.doi.org/10.1002/jbio.201900200en_US
dc.identifier.urihttp://hdl.handle.net/11536/153476-
dc.description.abstractThe delineation of brain tumor margins has been a challenging objective in neurosurgery for decades. Despite the development of various preoperative imaging techniques, the current methodology is still insufficient for clinical practice. We present an intraoperative optical intrinsic signal imaging system for brain tumor surgery and establish a data processing procedure model to localize tumors. From the experimental result of a glioblastoma patient, we observe a relative small oscillation of Delta HbD in tumor region and speculate that vessels in tumor region have poor ability to provide oxygen. We applied the same data processing procedure on the second time data and proclaimed a successful surgery. Figure: Merged Delta HbD image captured prior and posterior to tumor removal.en_US
dc.language.isoen_USen_US
dc.subjectbrain tumor surgeryen_US
dc.subjectoptical intrinsic signalen_US
dc.subjectsurgery guidingen_US
dc.titleNeurosurgical brain tumor detection based on intraoperative optical intrinsic signal imaging technique: A case report of glioblastomaen_US
dc.typeArticleen_US
dc.identifier.doi10.1002/jbio.201900200en_US
dc.identifier.journalJOURNAL OF BIOPHOTONICSen_US
dc.citation.volume13en_US
dc.citation.issue1en_US
dc.citation.spage0en_US
dc.citation.epage0en_US
dc.contributor.department交大名義發表zh_TW
dc.contributor.departmentNational Chiao Tung Universityen_US
dc.identifier.wosnumberWOS:000505520900010en_US
dc.citation.woscount0en_US
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