標題: One-Pot Synthesis of Unsymmetrical Bis-Heterocycles: Benzimidazole-, Benzoxazole-, and Benzothiazole-Linked Thiazolidines
作者: Lu, Hsueh-Yuan
Barve, Indrajeet J.
Selvaraju, Manikandan
Sun, Chung-Ming
應用化學系
Department of Applied Chemistry
關鍵字: benzimidazoles;combinatorial chemistry;molecular diversity;microwave irradiation;one-pot reaction;three-component synthesis
公開日期: 1-一月-2020
摘要: A one-pot, three-component synthesis of benzimidazole-linked thiazolidines from 2-cyanomethyl benzimidazole, iso-, isothio-, or isoselenocyanates and 1,2-dichloroethane is reported. Isolation of the key intermediate formed during the course of the reaction validates its mechanistic pathway. Under the same reaction conditions, benzimidazole-linked/fused thiazinanes were obtained when 1,3-dichloropropane or diiodomethane was used.
URI: http://dx.doi.org/10.1021/acscombsci.9b00161
http://hdl.handle.net/11536/153554
ISSN: 2156-8952
DOI: 10.1021/acscombsci.9b00161
期刊: ACS COMBINATORIAL SCIENCE
Volume: 22
Issue: 1
起始頁: 42
結束頁: 48
顯示於類別:期刊論文