多維度的細胞分化在數學上的研究

Abstract

我們分析並總結在文獻裡提到的三個細胞分化模型的數學特性。這些數學模型描述細胞分化過程中ㄧ些相關蛋白質與基因表現控制網路中多重開關之動態。這些系統是可由多個對抗性分部所組成，在基因控制中，每一分部各以全有或無之方式引導細胞分化成特定之形式。

We summarize mathematical properties for three cellular differentiation models proposed in the literatures. These mathematical models are used to describe basic multi-switching dynamics in generic master regulatory networks. These systems consist of arbitrary number of antagonistic components which direct differentiation in an all-or-none fashion to a specific cell-type chosen in gene regulation.